Endocrine Abstracts

BackgroundType 2 diabetes has traditionally been considered a disease affecting older age groups. In recent years, however, Type 2 diabetes has become increasingly common in children, adolescents and young adults.Aim of the workTo estimate the prevalence of T2D among a sample of Egyptian youth aged (18–30) and to highlight the challenges in differentiating T1D from T2D in early onset diabetes depending o...

Introduction: Irisin is a myokin secreted by myocytes responsible for transmission of signals from muscles to other body tissues. It improves systemic metabolism by increasing energy expenditure and has a significant influence on the body metabolism and thermogenesis. Thyroid disorders are characterized by a disrupted thermo-metabolic state and muscular damage, and the underlying mechanisms still not clear.Aim: To evaluate serum Irisin levels in patient ...

Introduction: Thyroid nodules are extremely common. By age 60, about one-half of all people have a thyroid nodule. Cryoablation is used in a variety of clinical applications, using hollow needles (cryoprobes). Cryoprobes are inserted into or placed adjacent to diseased tissue which is desired to be ablated.Objectives: To evaluate the effect of Cryoablation on the size & function of thyroid nodule, which may replace the need for surgery or radiotherap...

Background: Diabetic retinopathy (DR) is a clinically well-defined sight-threatening complication in type 2 diabetes. Angiopoietin 1 (Ang1) has been shown to promote endothelial cell survival without causing proliferation, stabilise endothelial interactions with surrounding support cells and can block the vascular permeability effects of vascular endothelial growth factor (VEGF). More recent data suggest that balance between these growth factors may affect vascular endothelial...

BackgroundVitamin D deficiency seems to be more prevalent among diabetic patients with distal symmetrical polyneuropathy. Besides, those patients have a lower pain threshold; there is a shortage of data concerning pre-diabetic individuals with peripheral neuropathy (PN).AimFirst, to study the association of vitamin D deficiency with PN severity. Second, to determine the effect of vitamin D supplementation on ...